EX-10.1
LEXICON PHARMACEUTICALS, INC.
1 1631165623.6 THE LOANS MAY HAVE BEEN ISSUED WITH “ORIGINAL ISSUE DISCOUNT” FOR U.S. FEDERAL INCOME TAX PURPOSES. [**] WILL MAKE AVAILABLE TO ANY LENDER: (1) THE AMOUNT OF ORIGINAL ISSUE DISCOUNT OF THE LOAN, (2) THE ISSUE PRICE OF THE LOAN, (3) THE ISSUE DATE OF THE LOAN AND (4) THE YIELD TO MATURITY OF THE LOAN UPON RECEIVING A WRITTEN REQUEST FOR SUCH INFORMATION. LOAN AND SECURITY AGREEMENT THIS LOAN AND SECURITY AGREEMENT is made and dated as of May 4, 2026 and is entered into by and among LEXICON PHARMACEUTICALS, INC., a Delaware corporation (“Company”), its Subsidiary LEXICON PHARMACEUTICALS (NEW JERSEY), INC., a Delaware corporation (“Lexicon Sub”), its Subsidiary LION ACQUISITION CORPORATION, a Delaware corporation (“Lion”), each other Person that has delivered a Joinder Agreement pursuant to Section 7.13 from time to time party hereto (together with Company, Lexicon Sub, and Lion individually or collectively, as the context may require, “Borrower”), the several banks and other financial institutions or entities from time to time party hereto (each, a “Lender”, and colle
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