EX-10.12
MADRIGAL PHARMACEUTICALS, INC.
ACTIVE/206697005.5 CERTAIN CONFIDENTIAL INFORMATION IN THIS EXHIBIT HAS BEEN OMITTED AND REPLACED WITH “[***]” BECAUSE IT IS NOT MATERIAL AND WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED. Exhibit 10.12 THIRD AMENDMENT AGREEMENT This THIRD AMENDMENT AGREEMENT (this “Agreement”), dated as of May 4, 2026, is entered into by and among MADRIGAL PHARMACEUTICALS, INC., a Delaware corporation (the “Borrower”), certain Subsidiaries of Borrower, as Guarantors (the “Guarantors”), the Lenders party hereto, and LSI FINANCING LLC, as administrative agent for the Lenders (in such capacity, the “Administrative Agent”). WHEREAS, the Borrower, certain Subsidiaries of Borrower, as Guarantors, the Lenders from time to time party thereto and the Administrative Agent have entered into that certain Financing Agreement, dated as of July 17, 2025 (as amended by that certain First Omnibus Amendment and Loan Party Joinder Agreement, dated as of September 4, 2025, as amended by that certain Second Amendment Agreement, dated as of December 30, 2025, and as further amended, restated, amended and resta
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