EX-10.21
Korsana Biosciences, Inc.
September 8, 2026
Matthew Leoni
[***]
[***]
Email: [***]
Re: Offer of Employment
Dear Matthew:
On behalf of Korsana Biosciences, Inc. (f/k/a Cyclerion Therapeutics, Inc., the “Company”), I am very pleased to offer you continued employment as Chief Medical Officer (the “Role”) pursuant to this letter agreement (the “Agreement”). This Agreement will amend and restate the June 5, 2026 letter agreement between you and Korsana Biosciences Operating Company, LLC (f/k/a Korsana Biosciences, Inc., “OpCo”), provided you accept such offer as indicated by your signature below, effective as of the consummation of the Company’s acquisition of OpCo (the “Effective Date”). You will be employed by OpCo, a subsidiary of the Company, and references to the Company with respect to your employing entity shall include OpCo.
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