Exhibit 10.1

Exhibit 10.1

908 Devices Inc.

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Non-Employee Director Compensation Policy

AMENDED AND RESTATED EFFECTIVE OCTOBER 29, 2026

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ThepurposeofthisNon-Employee DirectorCompensationPolicy (the “Policy”) of908 Devices Inc.(the“Company”)isto provideatotalcompensationpackagethatenablestheCompany toattractandretain,onalong-termbasis,high-caliberdirectorswhoarenotemployeesorofficersoftheCompany orits subsidiaries (“non-employee directors”). Infurtherance ofthepurpose statedabove,allnon-employee directorsshallbe paid compensation for services provided to theCompanyas set forth below:

Cash Retainers

Annual* Retainer for Board** Membership*: $40,000 forgeneralavailabilityandparticipationin meetings andconferencecalls of ourBoard of Directors, to be paid quarterly in arrears, pro-rated based on the number of actual days served by the director during such calendar quarter. No additional compensation will be paid for attending individual meetings of the Board of Directors.

Additional Annual Retainer for Non-Executive Chair:  $50,000

*Additional Annual Retainers for Committee Membership*:

Audit CommitteeChair:$20,000

Audit Committeemember:$10,000

Compensation CommitteeChair:$20,000

Compensation Committeemember:$10,000

Nominatingand Corporate GovernanceCommitteeChair:$15,000

Nominatingand Corporate GovernanceCommitteemember:$7,500

Chair and committee member retainers are inadditiontoretainersformembersoftheBoardofDirectors. No additional compensation will be paid for attending individual committee meetings of the Board of Directors.

*Equity Retainers*

Initial Award: An initial, one-time equity award (the “Initial Award”), representing $200,000 of value on the grant date, will be granted to each new non-employee director upon his or her election to the Board of Directors, with 75% of the value allocated to Restricted Stock Unit awards (“RSUs”), and 25% of the value allocated to Non-Qualified Stock Option awards (“NQSOs”).

The number of RSUs issued shall be calculated by dividing $150,000 by the closing market price on the NASDAQ Global Market (or such other market on which the Company’s common stock is then principally listed) of a share of the Company’s common stock on the effective date of grant, and rounding up to the next whole number of shares.

The number of NQSOs granted shall be calculated by dividing $50,000 by the fair value calculated under ASC Topic 718 (i.e., Black-Scholes Value) of an option to purchase a share of the Company’s common stock on the effective date of grant, and rounding up to the next whole number of shares. The NQSOs subject to the Initial Award shall expire ten years from the date of grant and the exercise price per share of such NQSOs shall be the closing market price on the NASDAQ Global Market (or such other market on which the Company’s common stock is then principally listed) of a share of the Company’s common stock on the effective date of grant.

The RSUs shall vest annually over three (3) years from the director commencement date, with pro rata vesting upon termination of service for any reason, and the NQSOs shall vest monthly over three (3) years from the director commencement date.

Annual Award: On or about the date of each Annual Meeting of Stockholders of the Company (the “Annual Meeting”), each continuing non-employee director, other than a director who joined the Board of Directors and received an Initial Award within 90 days of such Annual Meeting, will receive an annual equity award (the “Annual Award”), representing $150,000 of value on the grant date, with 75% of the value allocated to RSUs, and 25% of the value allocated to NQSOs.

The number of RSUs issued shall be calculated by dividing $112,500 by the closing market price on the NASDAQ Global Market (or such other market on which the Company’s common stock is then principally listed) of a share of the Company’s common stock on the effective date of grant, and rounding up to the next whole number of shares.

The number of NQSOs granted shall be calculated by dividing $37,500 by the fair value calculated under ASC Topic 718 (i.e., Black-Scholes Value) of an option to purchase a share of the Company’s common stock on the effective date of grant, and rounding up to the next whole number of shares. The NQSOs subject to the Annual Award shall expire ten years from the date of grant and the exercise price per share of such NQSOs shall be the closing market price on the NASDAQ Global Market (or such other market on which the Company’s common stock is then principally listed) of a share of the Company’s common stock on the effective date of grant.

The RSUs shall vest in full at the one year anniversary of the Annual Meeting, or the day prior to the next Annual Meeting, whichever is first to occur, with pro rata vesting upon termination of service for any reason, and the NQSOs shall vest monthly over one (1) year from the date of the Annual Meeting.

Sale Event Acceleration: All outstanding Initial Awards and Annual Awards held by a non-employee director shall become fully vested and exercisable upon a Sale Event (as defined in the Company’s 2020 Stock Option and Incentive Plan).

Expenses

TheCompanywillreimburseallreasonableout-of-pocketexpensesincurredbynon-employee directors in attendingmeetings of theBoard of Directors oranycommittee thereof.

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ADOPTED:November 23, 2020