Exhibit 10.2
CERTAIN INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY "[***]," HAS BEEN OMITTED BECAUSE IT IS BOTH (1) NOT MATERIAL AND (II) THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL.
| AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT | 1. CONTRACT ID CODE | PAGE OF PAGES | |||||||
| 1 | 12 | ||||||||
| 2. AMENDMENT/MODIFICATION NO. P00020 | 3. EFFECTIVE DATE See Block 16C | 4. REQUISITION/PURCHASE REQ. NO. See Schedule | 5. PROJECT NO. (If applicable) | ||||||
| 6. ISSUED BY | CODE | ASPR-BARDA | 7. ADMINISTERED BY (If other than Item 6) | CODE | |||||
| ASPR-BARDA 200 Independence Ave., S.W. Room 640-G Washington DC 20201 | |||||||||
| 8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, State and ZIP Code) SIGA TECHNOLOGIES, INC. 1385150 Attn: DANIEL J. LUCKSHIRE SIGA TECHNOLOGIES, INC. 31, EA 31, EAST 62ND STREET NEW YORK NY 10065 | (x) | 9A. AMENDMENT OF SOLICITATION NO. | |||||||
| 9B. DATED (SEE ITEM 11) | |||||||||
| x | 10A. MODIFICATION OF CONTRACT/ORDER NO. HHSO100201800019C | ||||||||
| 10B. DATED (SEE ITEM 13) 09/10/2018 | |||||||||
| CODE 1385150 | FACILITY CODE | ||||||||
| 11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS | |||||||||
| ☐ The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers ☐ is extended, ☐ is not extended. Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended , by one of the following methods: (a) By completing Items 8 and 15, and returning * * copies of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted ; or (c) By separate letter or electronic communication which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGEMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by letter or electronic communication, provided each letter or electronic communication makes reference to the solicitation and this amendment, and is received prior to the opening hour and date specified. | |||||||||
| 12. ACCOUNTING AND APPROPRIATION DATA (If required) 2026.Q990133.25106 | Net Increase: | $2,068,321.00 | |||||||
| 13. THIS ITEM ONLY APPLIES TO MODIFICATION OF CONTRACTS/ORDERS. IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14. | |||||||||
| CHECK ONE | A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: *(Specify authority) *THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A. | ||||||||
| B. THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES *(such as changes in paying office, appropriation data, etc.) * SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b). | |||||||||
| C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF: | |||||||||
| X | D. OTHER (Specify type of modification and authority) FAR 43.103(a) Modification by mutual agreement of the parties. | ||||||||
| E. IMPORTANT: | Contractor | ☒ is not | is required to sign this document and return * * copies to the issuing office. | ||||||
| 14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.) Tax ID Number: 13-3864870 UEI: VJRNRTSL22K4 The purpose of this modification is to provide supplemental funding to CLIN000l removing red dye from the Tecovirimat capsules following the Food and Drug Administration (FDA) ban of using red dye in ingested drugs, published as "FDA to Revoke Authorization for the Use of Red No. 3 in Food and Ingested Drugs", update Article B.2 Base Period, Article G.2. Contracting Officer's Representative, G.4. Key Personnel, and Section J - List of Attachments, Attachment 2, Statement of Work. The total obligated amount is increased by $2,068,321.00 from $624,438,549.00 to $626,506,870.00. Continued ... Except as provided herein, all terms and conditions of the document referenced in Item 9 A or 10A, as heretofore changed, remains unchanged and in full force and effect. | |||||||||
| 15A. NAME AND TITLE OF SIGNER (Type or print) Dennis Hruby, Chief Scientific Officer | 16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print) AUDREY A. GLOVER | ||||||||
| 15B. CONTRACTOR/OFFEROR /s/ Dennis Hruby | 15C. DATE SIGNED | 16B. UNITED STATES OF AMERICA /s/ Audrey A. Glover | 16C. DATE SIGNED | ||||||
| (Signature of person authorized to sign) | August 7, 2026 | (Signature of Contracting Officer) | August 7, 2026 | ||||||
| CONTINUATION SHEET | REFERENCE NO. OF DOCUMENT BEING CONTINUED HHSO100201800019C/P00020 | PAGE OF | |||
| 2 | 12 | ||||
| NAME OF OFFEROR OR CONTRACTOR SIGA TECHNOLOGIES, INC. 1385150 | |||||
| ITEM NO. (A) | SUPPLIES/SERVICES (B) | QUANTITY (C) | UNIT (D) | UNIT PRICE (E) | AMOUNT (F) |
| All other terms and conditions remain unchanged. OTA: N Discount Terms: HHS NET 30P Appr. Yr.: 2026 CAN: Q990133 Object Class: 25106 Period of Performance: 09/10/2019 to 09/09/2028 Add Item 23 as follows: | |||||
| 23 | CLIN0001 Late-Stage development activities toward FDA approval for parenteral (IV) antiviral Period of Performance: 9/10/2019-9/9/2028 Obligated Amount: $2,068,321.00 Requisition No: ASP351338 | 2,068,321.00 | |||
Section B –** Supplies or Services and Prices/Costs**
Article B.2 Base Period is deleted and replaced as follows:
| Base Period Cost Reimbursement CLIN | |||||
| Item | Period of Performance | Supplies/Services | Estimated Cost | Fixed Fee | Cost + Fixed Fee (CPFF) |
| 0001 Base | [***] | Late-stage development activities toward FDA approval for parenteral (IV) antiviral | [***] | [***] | [***] |
| Total (CLIN0001) | [***] | [***] | [***] |
| Base Period Fixed CLINs | |||||
| Item | Period of Performance | Supplies/Services | Unit (# of Doses or Dose Equivalents) | Unit Price ($) | Total ($) |
| 0002 Base | [***] | Initial purchase and delivery of nonparenteral (oral) formulated antiviral as the final drug product (FDP) to SNS | [***] | [***] | [***] |
| 0003 Base | [***] | Initial procurement of parenteral (IV) formulated antiviral as bulk drug substance (BDS) *TC = 28 vials | [***] | [***] | [***] |
| 0004 Base | [***] | Fill/finish of final drug product (from bulk drug substance procured under CLIN0003) | [***] | [***] | [***] |
| 0005 Base | [***] | Storage of final drug product in VMI for 5 years (from bulk drug substance procured under CLIN0003) *Monthly rate TC = [***] | [***] | [***] | [***] |
| 0006 Base | [***] | Delivery of FDP to the SNS (from bulk drug substance procured under CLIN0003 and Process Validation lot manufactured under CLIN0001) | [***] | [***] | [***] |
| Total (CLINs 0002-0006) | [***] |
| Optional Cost Reimbursement CLINs | |||||
| Item | Period of Performance | Supplies/Services | Estimated Cost | Fixed Fee | Cost + Fixed Fee (CPFF) |
| 0007 (Option Funded) | [***] | Phase IV post- marketing commitments (nonparenteral (oral) formulation) including [***] | [***] | [***] | $14,612,790 (Funded) |
| 0008 (Option Funded) | [***] | Phase IV Post Marketing commitments (parenteral (IV) formulation)) including [***] | [***] | [***] | $3,586,806 (Funded) |
| Total (CLINs 0007-0008) | [***] | [***] | [***] |
| Optional Fixed CLINs | |||||
| Item | Period of Performance | Supplies/Services | Treatment Courses (# of Product) | Unit Price ($) | Total ($) |
| 0009A (Option Funded) | [***] | Procurement of raw materials used in the manufacturing of unmicronized API in sufficient quantity to support the production of [***] courses of nonparenteral (oral) formulated antiviral for SNS replenishment. Such raw materials may be forward processed. | 363,070 (raw material) | [***] | $11,255,170 (Funded) |
| 0009B (Option Funded) | [***] | Additional procurement of nonparenteral (oral) formulated antiviral as FDP and delivery to the SNS | 121,023 (raw material) | [***] | $33,765,417 (Funded) |
| 0009C (Option Funded) | [***] | Additional procurement of nonparenteral (oral) formulated antiviral as FDP and delivery to the SNS | 121,023 (raw material) | [***] | $33,765,417 (Funded) |
| 0009D (Option Funded) | [***] | Additional procurement of nonparenteral (oral) formulated antiviral as FDP and delivery to the SNS | 121,024 (raw material) | [***] | $33,765,696 (Funded) |
| 0010 (Option Funded) | [***] | Additional procurement of nonparenteral (oral) formulated antiviral as FDP and delivery to the SNS | 363,070 | [***] | $112,551,700 (Funded) |
| 0011 (Option) | [***] | Additional procurement of nonparenteral (oral) formulated antiviral as FDP and delivery to the SNS | 363,070 | [***] | $112,551,700 (Funded) |
| 0012 (Option Funded) | [***] | Additional procurement of a nonparenteral (oral) formulated antiviral as FDP and delivery to SNS | 363,072 | [***] | $112,552,320 (Funded) |
| 0013 (Option Funded) | [***] | Surge Capacity – Additional procurement of parenteral (IV) formulated antiviral as bulk drug substance (BDS) *TC = [***] vials | 32,000 | [***] | $10,240,000 (Funded) |
| 0014 (Option) | [***] | Surge Capacity – Storage of parenteral (IV) formulated antiviral as bulk drug substance (BDS) in VMI for 5 years (from bulk drug substance procured under CLIN0013). *Monthly rate per TC = [***] | 32,000 | [***] | [***] |
| 0015 (Option Funded) | [***] | Surge Capacity Fill/finish of final drug product (from bulk drug substance procured under CLIN0013) | 32,000 | [***] | $15,360,000 (Funded) |
| 0016 (Option) | [***] | Surge Capacity – Storage of final drug product in VMI for 5 years (from bulk drug substance procured under CLIN0013). *Monthly rate per TC = [***] | 32,000 | [***] | [***] |
| 0017 (Option Funded) | [***] | Surge Capacity – Delivery of FDP to the SNS (from bulk drug substance procured under CLIN0013) | 32,000 | [***] | [***] |
| 0018 (Option Funded) | [***] | Surge Capacity – Additional procurement of parenteral (IV) formulated antiviral as bulk drug substance (BDS) *TC = [***] vials | 32,000 | [***] | $10,240,000 (Funded) |
| 0019 (Option) | [***] | Surge Capacity – Storage of parenteral (IV) formulated antiviral as bulk drug substance (BDS) in VMI for 5 years (from bulk drug substance procured under CLIN0018). *Monthly rate per TC = [***] | 32,000 | [***] | [***] |
| 0020 (Option Funded) | [***] | Surge Capacity Fill/finish of final drug product from bulk drug substance procured under CLIN0018) | 32,000 | [***] | $15,360,000 (Funded) |
| 0021 (Option) | [***] | Surge Capacity – Storage of final drug product in VMI for 5 years (from bulk drug substance procured under CLIN0018). *Monthly rate per TC = [***] | 32,000 | [***] | [***] |
| 0022 (Option Funded) | [***] | Surge Capacity – Delivery of FDP to the SNS (from bulk drug substance procured under CLIN0018). | 32,000 | [***] | [***] (Funded) |
| 0023 (Funded Option) | [***] | Surge Capacity – Additional procurement of parenteral (IV) formulated antiviral as bulk drug substance (BDS) *TC = [***] vials | 32,000 | [***] | $10,240,000 |
| 0024 (Option) | [***] | Surge Capacity – Storage of parenteral (IV) formulated antiviral as bulk drug substance (BDS) in VMI for 5 years (from bulk drug substance procured under CLIN0023). *Monthly rate per TC = [***] | 32,000 | [***] | [***] |
| 0025 (Funded Option) | [***] | Surge Capacity Fill/finish of final drug product (from bulk drug substance procured under CLIN0023) | 32,000 | [***] | $15,360,000 |
| 0026 (Option) | [***] | Surge Capacity – Storage of final drug product in VMI for 5 years (from bulk drug substance procured under CLIN0023). *Monthly rate per TC: [***] | 32,000 | [***] | [***] |
| 0027 (Funded Option) | [***] | Surge Capacity – Delivery of FDP to the SNS (from bulk drug substance procured under CLIN0023). | 32,000 | [***] | [***] |
| Total (CLINs ** 0009A – ** 0027) | [***] | ||||
| Total Contract Value | [***] | ||||
| Total Funded | [***] |
Article G.2. CONTRACTING OFFICER'S REPRESENTATIVE
The following Contracting Officer's Representative (COR) will represent the Government for the purpose of this contract:
Primary Contracting Officer's Representative (COR)
Olivia Molinar-Inglis
Contracting Officer's Representative
Center for the Biomedical Advanced Research and Development Authority (BARDA)
Office of the Assistant Secretary for Preparedness and Response
Department of Health and Human Services
Email: Oliva.Molinar-Inglis@hs.gov
Phone: (202) 205-2820
***Alternate Contracting Officer's Representative (ACOR) ***
Christina Son
Alternate Contracting Officer's Representative (ACOR)
Center for the Biomedical Advanced Research and Development Authority (BARDA)
Office of the Assistant Secretary for Preparedness and Response
Department of Health and Human Services
Email: Christina.Son@hhs.gov
Phone: (202) 692-4621
The COR is responsible for:
a. Monitoring the Contractor's technical progress, including the surveillance and assessment of performance, and recommending to the Contracting Officer changes in requirements.
b. Assisting the Contracting Officer in interpreting the statement of work and any other technical performance requirements.
c. Performing technical evaluation as required.
d. Performing technical inspections and assisting the Contracting Officer in acceptance of
deliverables required by this contract.
e. Assisting in the resolution of technical problems encountered during performance.
f. The Government may unilaterally change its COR designation(s).
Article G.4 KEY PERSONNEL
The following Key Personnel will represent the Contractor for the purpose of this contract:
The key personnel specified in this contract are considered to be essential to work performance. At least 30 days prior to the contractor voluntarily diverting any of the specified individuals to other programs or contracts the Contractor shall notify the Contracting Officer and shall submit a justification for the diversion or replacement and a request to replace the individual. The request must identify the proposed replacement and provide an explanation of how the replacement's skills, experience, and credentials meet or exceed the requirements of the contract (including, when applicable, Human Subjects Testing requirements). If the employee of the contractor is terminated for cause or separates from the contractor voluntarily with less than thirty (30) days' notice, the Contractor shall provide the maximum notice practicable under the circumstances. The Contractor shall not divert, replace, or announce any such change to key personnel without the written consent of the Contracting Officer. The contract will be modified to add or delete key personnel as necessary to reflect the agreement of the parties.
The following individual(s) is/are considered to be essential to the work being performed hereunder:
| Functional Area | Name |
| Principal Investigator | Dennis Hraby, Executive Vice President, Chief Scientific Officer |
| Clinical Development Lead | Emily Blum, Director, Clinical Development |
| Quality Assurance Lead | Kristin Murray, Senior Vice President, Regulatory and Quality |
| Supply Chain Lead | Tove' Bolken, Senior Vice President, Chief Supply Chain Officer |
| Regulatory Lead | Paul Long, Senior Director, Regulatory Affairs |
| Program Management | Kady Honeychurch, Director, Project Management |
| Manufacturing Lead | Steven Vicik, Chief Technical Officer |
| Pharmacovigilance Lead | Emily Blum, Director, Clinical Development |
Section J –** List of Attachments, Attachment 2, Statement of Work is deleted and replaced as follows:**
Contract HHSO100201800019C
Modification 0019
Statement of Work
The scope of this proposal includes the following activities:
| 1. | CLIN0001 (Funded Base): IV formulation process validation, pediatric formulation development to NDA, pediatric formulation packaging development, pediatric formulation clinical study formulation development, pediatric formulation pharmacokinetic clinical study conduct, regulatory support through pediatric formulation NDA, environmental studies, DDI phosphate binder study conduct, establish BDS CMO backup, labor, material procurement |
1.1. CLIN0001 (Contract mod 0018): Tech transfer of previously completed GMP manufacturing to new facility, material procurement, engineering and process validation batches, regulatory, labor, shipping of final deliverable to SNS
Deliverable: Process validation batches
1.2. CLIN0001 (Contract mod 0019 This contract mod): Completion of remaining CMC, Clinical, and Regulatory tasks in support of NDA filing for the Pediatric Oral Suspension formulation including manufacture of process validation batches, clinical study conduct, application submission to FDA, labor, and shipping of the process validation batches to the SNS
Deliverable: Process validation batches
1.3. CLIN0001 (This contract mod): Regulatory document compilation, writing, reviewing, submission, and responses to FDA questions applicable to removal of all dyes from the TPOXX capsules. Note that SIGA retains ownership of the TPOXX capsule batches manufactured for this purpose.
| 2. | CLIN0002 (Funded Base): Immediate delivery of [***] treatment courses of oral formulation |
| 3. | CLIN0003 (Funded Base): |
Procurement of [***] treatment courses of BDS for the manufacturing of IV TPOXX}
| 4. | CLIN0004 (Funded Base): Fill/finish of final drug product (from bulk drug substance procured under CLIN0003) |
| 5. | CLIN0005 (Funded Base): Storage of final drug product in VMI for 5 years (from bulk drug substance procured under CLIN0003) |
| 6. | CLIN0006 (Funded Base): Delivery of FDP to the SNS (from bulk drug substance procured under CLIN0003 and Process Validation lot manufactured under CLIN0001) |
| 7. | CLIN0007 (Funded Option): Emergency use support for non-smallpox disease, susceptibility studies, oral TPOXX field study set-up and close-out, pharmacokinetic study in subjects weighting more than 120 kg, pediatric formulation SAD study conduct; oral post marketing commitment responses, oral TPOXX life cycle management and support for oral TPOXX FDA requests, labor |
7.1 CLIN 0007 (Contract mod 003): Pediatric formulation pharmacokinetic clinical study protocol, pharmacokinetic study in subjects weighting more than 120 kg protocol, pediatric formulation SAD Study protocol and start-up, start-up pediatric formulation development, labor
| 8. | CLIN0008 (Funded Option): Phase 4 IV TPOXX Post Marketing Commitments, IV TPOXX life cycle management and support for IV TPOXX FDA requests, labor |
| 9. | CLIN0009A (Funded Option): Procurement of raw materials used in manufacturing of unmicronized API in sufficient quantity to support the production of 363,070 treatment courses of oral antiviral for SNS |
| 10. | CLIN0009B (Funded Option): Additional procurement of 121,023 treatment courses of oral antiviral as FDP and delivery to the SNS |
| 11. | CLIN0009C (Funded Option): Additional procurement of 121,023 treatment courses of oral antiviral as FDP and delivery to the SNS |
| 12. | CLIN0009D (Funded Option): Additional procurement of 121,023 treatment courses of oral antiviral as FDP and delivery to the SNS |
| 13. | CLIN0010 (Funded Option): Procurement and delivery of up to 363,070 treatment courses of oral TPOXX to SNS |
| 14. | CLIN0012 (Funded Option): Procurement and delivery of up to 363,072 treatment courses of oral TPOXX to SNS |
| 15. | CLIN0013 (Funded Option): Procurement of 32,000 treatment courses of IV formulated antiviral as BDS |
| 16. | CLIN0014 (Option): Storage of 32,000 treatment courses of IV formulated antiviral BDS in VMI for 5 years |
| 17. | CLIN0015 (Funded Option): Manufacture/fill/package/stability of 32,000 treatment courses of IV TPOXX from BDS procured under CLIN0013 |
| 18. | CLIN0016 (Option): Storage of 32,000 treatment courses of IV TPOXX FDP in VMI for 5 years |
| 19. | CLIN0017 (Funded Option): Delivery of 32,000 treatment courses of IV FDP to SNS |
| 20. | CLIN0018 (Funded Option): Procurement of 32,000 treatment courses of IV formulated antiviral as BDS |
| 21. | CLIN0019 (Option): Storage of 32,000 treatment courses of IV formulated antiviral BDS in VMI for 5 years |
| 22. | CLIN0020 (Funded Option): Manufacture/fill/package/stability of 32,000 treatment courses of IV TPOXX from BDS procured under CLIN0018 |
| 23. | CLIN0021 (Option): Storage of 32,000 treatment courses of IV TPOXX FDP in VMI for 5 years |
| 24. | CLIN0022 (Funded Option): Delivery of 32,000 treatment courses of IV FDP to SNS |
| 25. | CLIN0023 (Funded Option): Procurement of 32,000 treatment courses of IV formulated antiviral as BDS |
| 26. | CLIN0024 (Option): Storage of 32,000 treatment courses of IV formulated antiviral BDS in VMI for 5 years |
| 27. | CLIN0025 (Funded Option): Manufacture/fill/package/stability of 32,000 treatment courses of IV TPOXX from BDS procured under CLIN0024 |
| 28. | CLIN0026 (Option): Storage of 32,000 treatment courses of IV TPOXX FDP in VMI for 5 years |
| 29. | CLIN0027 (Funded Option): Delivery of 32,000 treatment courses of IV FDP to SNS |
The objectives of this modification are:
| 1) | To compile all necessary documentation from SIGA's Contract Manufacturing Organizations describing the change from orange and black capsules to clear capsules. |
| 2) | To write and review the required eCTD sections to support the change to the capsule appearance. |
| 3) | To submit a Prior Approval Supplement to the FDA for review and comment. |
The final deliverable is:
| 1) | FDA approval of the change in capsule from orange and black to clear. |
Detailed Breakdown of the activities funded under CLIN 0001 in this modification:
1. Consultant support
2. SIGA labor
All other terms and conditions of this contract remain unchanged and in full force and effect.
END OF MODIFICATION P00020 to HHSO100201800019C